WebMD explains pelvic organ prolapse, a condition in which pelvic muscles can no longer adequately In this Article Pelvic organ prolapse, a type of pelvic floor disorder, can affect many women. In fact . Women's Health. Nonsurgical (conservative) management of pelvic organ prolapse is recommended by both the Agency for Health Care Policy and Research. Pelvic organ prolapse (POP). When the muscles and ligaments supporting a woman's pelvic organs weaken, the pelvic organs can slip out of place (prolapse).